Statistical information is an important tool for understanding and quantifying the impact of political decisions in a specific territory or region. The Eurostat regional yearbook 2020 provides a detailed picture relating to a broad range of statistical topics across the regions of the EU Member States, as well as the regions of the United Kingdom, the EFTA and candidate countries. Each chapter presents statistical information in the form of maps, figures and infographics, accompanied by a descriptive analysis highlighting the main findings. Regional indicators are presented for the following 13 subjects: population, health, education, the labour market, living conditions, the economy, business, research and innovation, the digital society, tourism, transport, the environment and agriculture.